• 04/12/2021
• 
• Knock  
• Kiltimagh/Knock
• 11:00
• Kiltimagh/Knock
• 11:00
• Ballaghaderren Fc
• Ballaghaderren Fc
• More +
• More +
Referee: Tom Jennings
Referee: Tom Jennings
Venue: Knock

• 04/12/2021
• 
• Ballina  
• Ballina Town
• 12:00
• Ballina Town
• 12:00
• Castlebar Celtic
• Castlebar Celtic
• More +
• More +
Referee: Jimmy Cawley
Referee: Jimmy Cawley
Venue: Ballina

• 04/12/2021
• 
• TBC  
• Benbulben FC
• 12:00
• Benbulben FC
• 12:00
• Partry Athletic
• Partry Athletic
• More +
• More +
Referee: TBC
Referee: TBC
Venue: TBC

• 04/12/2021
• 
• TBC  
• Colga FC
• 12:00
• Colga FC
• 12:00
• Manulla
• Manulla
• More +
• More +
Referee: TBC
Referee: TBC
Venue: TBC

• 04/12/2021
• 
• Manulla  
• Manulla B
• 12:00
• Manulla B
• 12:00
• Strand Celtic
• Strand Celtic
• More +
• More +
Referee: Declan Kavanagh
Referee: Declan Kavanagh
Venue: Manulla

• 04/12/2021
• 
• Milebush Park  
• Mayo
• 12:00
• Mayo
• 12:00
• Galway
• Galway
• More +
• More +
Referee: TBC
Referee: TBC
Venue: Milebush Park

• 04/12/2021
• 
• Westport  
• Westport Utd B
• 12:00
• Westport Utd B
• 12:00
• Moyne Villa
• Moyne Villa
• More +
• More +
Referee: Ronan Walsh
Referee: Ronan Walsh
Venue: Westport

• 04/12/2021
• 
• Knock  
• Kiltimagh/Knock
• 12:30
• Kiltimagh/Knock
• 12:30
• Mervue
• Mervue
• More +
• More +
Referee: Allan English
Referee: Allan English
Venue: Knock

• 04/12/2021
• 
• Ballinrobe  
• Ballinrobe
• 14:00
• Ballinrobe
• 14:00
• Merlin Woods
• Merlin Woods
• More +
• More +
Referee: Vincent Joyce
Referee: Vincent Joyce
Venue: Ballinrobe

• 04/12/2021
• 
• TBC  
• Ballygawley Celtic
• 14:00
• Ballygawley Celtic
• 14:00
• Manulla B
• Manulla B
• More +
• More +
Referee: TBC
Referee: TBC
Venue: TBC

• 04/12/2021
• 
• Claremorris  
• Claremorris
• 14:00
• Claremorris
• 14:00
• Ballisodare United
• Ballisodare United
• More +
• More +
Referee: Pearse Concannon
Referee: Pearse Concannon
Venue: Claremorris

• 04/12/2021
• 
• Galway  
• Colga FC
• 14:00
• Colga FC
• 14:00
• Killala
• Killala
• More +
• More +
Referee: TBC
Referee: TBC
Venue: Galway

• 04/12/2021
• 
• Galway  
• Colga FC
• 14:00
• Colga FC
• 14:00
• Newport Mulranny Wanderers
• Newport Mulranny Wanderers
• More +
• More +
Referee: TBC
Referee: TBC
Venue: Galway

• 04/12/2021
• 
• TBC  
• Manor Rangers
• 14:00
• Manor Rangers
• 14:00
• Westport Utd D
• Westport Utd D
• More +
• More +
Referee: TBC
Referee: TBC
Venue: TBC

• 04/12/2021
• 
• Westport  
• Westport Utd
• 14:00
• Westport Utd
• 14:00
• Athenry
• Athenry
• More +
• More +
Referee: Aiden Dunleavy
Referee: Aiden Dunleavy
Venue: Westport

• 04/12/2021
• 
• Knock  
• Kiltimagh/Knock
• 14:30
• Kiltimagh/Knock
• 14:30
• Loughrea
• Loughrea
• More +
• More +
Referee: Aiden Nevin
Referee: Aiden Nevin
Venue: Knock

• 04/12/2021
• 
• Milebush Park  
• Mayo
• 14:30
• Mayo
• 14:30
• Wexford
• Wexford
• More +
• More +
Referee: TBC
Referee: TBC
Venue: Milebush Park

• 04/12/2021
• 
• TBC  
• Moyne Villa
• 18:30
• Moyne Villa
• 18:30
• Westport Utd C
• Westport Utd C
• More +
• More +
Referee: TBC
Referee: TBC
Venue: TBC

• 05/12/2021
• 
• Claremorris  
• Claremorris
• 12:00
• Claremorris
• 12:00
• Ballina Town
• Ballina Town
• More +
• More +
Referee: Adrian Redmond
Referee: Adrian Redmond
Venue: Claremorris

• 05/12/2021
• 
• Manulla  
• Manulla
• 12:00
• Manulla
• 12:00
• Melview Celtic
• Melview Celtic
• More +
• More +
Referee: Aiden Nevin
Referee: Aiden Nevin
Venue: Manulla

• 05/12/2021
• 
• Merview United  
• Merview United
• 12:00
• Merview United
• 12:00
• Killala
• Killala
• More +
• More +
Referee: TBC
Referee: TBC
Venue: Merview United

• 05/12/2021
• 
• Galway  
• Galway Bohs
• 12:30
• Galway Bohs
• 12:30
• Castlebar Celtic
• Castlebar Celtic
• More +
• More +
Referee: TBC
Referee: TBC
Venue: Galway

• 05/12/2021
• 
• Abbeyfeale Utd  
• Kenagh United
• 12:30
• Kenagh United
• 12:30
• Claremorris
• Claremorris
• More +
• More +
Referee: TBC
Referee: TBC
Venue: Abbeyfeale Utd

• 05/12/2021
• 
• Cregmore  
• Cregmore
• 14:00
• Cregmore
• 14:00
• Claremorris B
• Claremorris B
• More +
• More +
Referee: TBC
Referee: TBC
Venue: Cregmore

• 05/12/2021
• 
• Galway  
• Mervue B
• 14:00
• Mervue B
• 14:00
• Claremorris
• Claremorris
• More +
• More +
Referee: TBC
Referee: TBC
Venue: Galway

• 05/12/2021
• 
• TBC  
• Newtown
• 14:00
• Newtown
• 14:00
• Westport Utd
• Westport Utd
• More +
• More +
Referee: TBC
Referee: TBC
Venue: TBC

• 05/12/2021
• 
• North Tipperary  
• North Tipperary
• 14:00
• North Tipperary
• 14:00
• Mayo
• Mayo
• More +
• More +
Referee: TBC
Referee: TBC
Venue: North Tipperary

• 05/12/2021
• 
• Westport  
• Renmore
• 14:00
• Renmore
• 14:00
• Westport Utd C
• Westport Utd C
• More +
• More +
Referee: TBC
Referee: TBC
Venue: Westport

• 05/12/2021
• 
• Galway  
• Salthill Devon
• 14:00
• Salthill Devon
• 14:00
• Castlebar Celtic
• Castlebar Celtic
• More +
• More +
Referee: TBC
Referee: TBC
Venue: Galway

• 11/12/2021
• 
• Athenry  
• Athenry
• 00:00
• Athenry
• 00:00
• Castlebar Celtic
• Castlebar Celtic
• More +
• More +
Referee: TBC
Referee: TBC
Venue: Athenry

• 11/12/2021
• 
• Green Road Foxford  
• Straide and Foxford
• 14:30
• Straide and Foxford
• 14:30
• Kiltimagh/Knock
• Kiltimagh/Knock
• More +
• More +
Referee: TBC
Referee: TBC
Venue: Green Road Foxford

• 12/12/2021
• 
• Claremorris  
• Claremorris
• 14:00
• Claremorris
• 14:00
• Castlebar Celtic
• Castlebar Celtic
• More +
• More +
Referee: TBC
Referee: TBC
Venue: Claremorris